OP Labs formerly Oxford PeptidesDesigned to specificationStore frozen long term or in fridge when ready to be usedSold for research purposes onlyContact us for Wholesale OrdersDownload COA here: Adamax_COA.pdfPlease note: if you have a different Batch ID, please contact us for the latest COA.ADAMAXSynonyms / Designations: Adamax, Adamantyl Acetyl Hexapeptide, Adamantane-modified acetyl hexapeptideCAS Number:80714-61-0Molecular Formula: C37H51N9O10SMolecular Weight: 854.97 g/mol Peptide Classification:Synthetic hexapeptide with adamantane lipid modificationPurity: Designed to specification (HPLC-characterised, typical)Appearance: White to off-white powderPack Size: 5 mg (total)Storage: Desiccated, protected from light, stored at –20Solubility: Soluble in DMSO and compatible aqueous buffers depending on formulationDescription & Research ContextADAMAX is a synthetic hexapeptide incorporating an adamantane moiety, developed for experimental investigation of peptide stability, membrane interaction, and peptide–receptor or peptide–protein interaction dynamics in in vitro research systems. The adamantyl modification is used as a structural tool to enhance lipophilicity and alter physicochemical behaviour relative to non-modified peptide analogues.In laboratory research settings, ADAMAX is utilised as a model compound for studying peptide modification strategies, formulation behaviour, and structure–function relationships in short bioactive peptides. Observed molecular effects are dependent on experimental design, concentration, and model system and are not indicative of defined biological or clinical outcomes.Applications in Research• Investigation of peptide modification and stability strategies• In vitro studies of short peptide structure–function relationships• Evaluation of lipid-modified peptide behaviour in formulation systems• Use as a reference compound in cosmetic or biochemical peptide researchHandling, Reconstitution & Stability• Handle under dry conditions; peptide is hygroscopic• Reconstitute in DMSO or suitable buffered aqueous system depending on assay design• Avoid vigorous agitation during dissolution• Aliquot reconstituted solutions to minimise freeze–thaw cycles• Store reconstituted solutions at –20 °C or lower for long-term stabilitySpecifications SummaryBatch tested Purity: ≥ 99 % (HPLC / SEC, typical)Appearance: White to off-white powderPeptide Type: Adamantane-modified synthetic hexapeptideMolecular Weight: 854.97 g/molSolubility: DMSO; buffered aqueous systems (formulation-dependent)Storage: –20 °C, desiccated, protected from lightPack Size: 5 mgPrecautions & Notes• Experimental behaviour may vary depending on solvent system and formulation• Lipid-modified peptides may exhibit altered aggregation or binding properties• Appropriate controls are recommended in all experimental designs• Intended strictly for laboratory research use only• Not for human or veterinary applicationReferencesŠtimac A. et al. Adamantane in drug delivery systems and surface recognition. Molecules, 2017.https://www.mdpi.com/1420-3049/22/2/297Wanka L. et al. The lipophilic bullet hits the targets: medicinal chemistry of adamantane derivatives. Chemical Reviews, 2013.https://pubmed.ncbi.nlm.nih.gov/23721347/Pramod M. et al. Adamantylglycine as a high-affinity peptide label for cucurbit[7]uril. Chemical Communications, 2024.https://pubs.rsc.org/en/content/articlehtml/2024/cc/d4cc00602jHe B. et al. Role of peptide–cell surface interactions in cosmetic peptide applications. Cosmetics, 2023.https://pubmed.ncbi.nlm.nih.gov/38027006/Keywords: ADAMAX, Adamantyl Acetyl Hexapeptide, Adamantane Peptide, Synthetic Cosmetic Peptide, Research Peptide
